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Skin aging: The skin's microbiome may play a key role


Introduction:

The skin's microbiome may play a key role in skin aging, according to a new study. Skin aging is the result of complex biochemical pathways and morphological alterations. The skin's microbiome is a diverse community of microorganisms (e.g., bacteria, fungi, and viruses) that live on human skin and contribute substantially to the overall health of this organ. Previous studies have suggested that certain microbial species (e.g., bacteria) could enhance the body's natural anti-aging mechanisms through various anti-aging signaling mechanisms.

The skin's microbiome has the potential to fight skin aging and promote healthy skin. While we can't stop the skin aging process but we can slow it down. One factor is the skin's microbiome — the microorganisms that live on our skin.





1- The skin is a huge organ of the human body

According to a new study, Skin aging is the result of complex biochemical pathways and morphological alterations. In their study, published in Nature Communications, researchers looked at how these microbes affect skin health as we age. They discovered that certain types of bacteria are more abundant on older than younger people's faces, including Corynebacterium species (found in hair follicles), Propionibacterium acnes (found on sebaceous glands), Staphylococcus epidermidis (found on skin-associated surfaces) and Staphylococcus saprophyticus (found around wounds).

The study involved testing the microbiomes of 50 healthy volunteers aged between 18 and 35 years old who had no history of skin conditions or atopic dermatitis (eczema). The team also tested their microbiomes after they were exposed to ultraviolet light (UV) from a tanning bed for eight hours per day for three days. The scientists found that people who spent more time in UV light had lower levels of vitamin D in their skin compared to those who only spent four hours per week under UV light or stayed indoors during sunbathing periods.


2- Aging is a natural process that affects all living organisms with the passage of time

We can minimize the effects of aging but not cancels the effects of aging. It is the progressive deterioration of an organism's structure and function caused by the accumulation of damage to cells, tissues, and organs. Aging is usually divided into three stages: youth, middle age, and old age (also known as senescence).

The aging process can be slowed down or even halted through a variety of techniques, but this does not mean that aging will stop completely. As we grow older our bodies gradually lose their ability to repair themselves. This means that the more damage you accumulate over time, the harder it will be for your body to repair itself and get back to normal function. The rate at which we age depends on many factors such as genetics and lifestyle habits like smoking cigarettes or drinking alcohol. However, there are some factors that have been proven to slow down or even halt aging such as exercise, eating healthy foods, and maintaining a balanced diet rich in vitamins A, C, and E.






3- Skin aging is a complex process that involves many different factors

Skin aging is a complex process that involves many different factors. It’s not just the age of your skin that determines its appearance, but also your genetics and lifestyle choices.

Skin aging is the result of changes in the skin's appearance and structure. Skin aging can be divided into two main categories: intrinsic and extrinsic, which refer to the cause of skin changes. Intrinsic causes include sun exposure, smoking, poor nutrition, and genetics, while extrinsic causes include pollution, ultraviolet radiation from sunlight or tanning beds, chemicals found in cosmetics and household products, excessive alcohol consumption, and hormone imbalance.

The most common intrinsic causes of skin aging are:


i) sun exposure: 

This is one of the most important causes of premature skin aging. Sun exposure causes premature pigmentation spots (also known as age spots), wrinkles, and other changes in the skin's appearance over time. The longer you stay in the sun without protecting your face with sunscreen or applying an anti-aging cream after your daily moisturizer application (which should be at least 15 minutes before going outdoors), the more damage your skin will suffer from harmful UV rays.


ii) Poor nutrition: 

When we eat unhealthy food or don't eat enough nutrients our body lacks essential vitamins and minerals essential for healthy cells that produce collagen.


iii) Genetics

Genetics also plays a role in skin aging as people with certain inherited conditions such as Vitiligo or Rosacea may see their skin change more dramatically than average. Environmental factors such as sun exposure and smoking can also accelerate the aging process.


4- While we can't get around the skin aging process, there are things we can do to slow it down

Here are some of the best ways to protect your skin from skin aging:


Exfoliate:

Use a gentle exfoliator twice a week — once in the shower and once after you've finished washing your face. You can use a cleanser designed for sensitive skin or a scrub that contains glycolic acids or alpha hydroxy acids (AHAs).


Moisturize:

A moisturizer with SPF should be part of your daily regimen to help prevent sun damage and premature aging. Find one that's non-comedogenic (won't clog pores) and suitable for sensitive skin.


Protect from environmental pollutants at home:

Wear protective clothing — hats, gloves, long sleeves, pants — when you're gardening or working outside in the yard. Stay out of tanning beds, which can cause wrinkles and discoloration over time.


Exercise regularly:

Exercise regularly for at least 30(thirty) minutes per day. Aim for cardio exercises three times per week, such as running, walking, or swimming. Strength training two times per week is also recommended.


Reduce Stress:

Keep your stress levels in check by doing things you enjoy (such as reading) or taking time out each day to relax — even just 15 minutes could improve your mood and help you avoid turning to unhealthy coping mechanisms such as smoking or overeating when you feel stressed or anxious






5- The skin's microbiome may play a key role in skin aging, according to a new study

Researchers found that the skin microbiome, or the collection of bacteria living on the surface of our bodies, can change over time and may contribute to age-related skin changes such as wrinkles and loss of elasticity. The research and its findings were published in the journal Science Translational Medicine.

The microbes that live on our skin help us defend against infection and defend against environmental toxins. However, the effects of these microbes on the skin may be more significant than we realized. Researchers have long suspected that your microbiome might play a role in skin aging, but until now there was no real proof.

A team of researchers from the University of California San Diego used genetic sequencing to analyze the DNA from the skin of more than 100 people over age 65 (the average age for this group). They found that people with more diverse microbiomes tended to have healthier skin than those who had less diverse microbiomes.

In humans, the number of bacteria living on our skin is estimated to be around 100 trillion - and it's thought that they help prevent infection and maintain healthy levels of moisture and oil production. However, this also means that they can cause problems when they're out of balance or don't function properly - like when you get a cold sore or use antibiotics too often.



6- The skin's microbiome has the potential to fight skin aging and promote healthy skin, thanks to its ability to regulate gene expression

The human microbiome is composed of all the microorganisms that exist on or inside us, including bacteria, viruses, fungi, and parasites. The skin's microbiome is one of the largest microbiomes in the body, making up about 10 percent of our total microbiome.

Skin cells called keratinocytes are responsible for forming the outermost layer of your epidermis, which is what you see on your skin. Keratinocytes are continually being replaced by new ones. In fact, it takes about 21 days for a new keratinocyte to form, according to the British Association of Dermatologists.


Conclusion:

It's clear that the future of fighting to age has a lot to do with the microbiome, and the skin is an important target. While plenty of questions still need to be answered, researchers are making progress in uncovering its mysteries and harnessing its power to promote healthier younger-looking skin.

Thus, the relationship between skin aging and the microbiome is cause for concern. Although further research is still needed, this study has demonstrated that a disturbed microbiome can contribute to skin-aging side effects. The mystery of how microflora affects the skin will likely continue for some time, but this study lays the groundwork for future research in this exciting new field of skin care.

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